There is no God or gods, there are no morals, the universe is not moving inexorably towards any higher purpose. All meaning is man-made, so make your own and make it well. Do not treat life as a way to pass the time until you die. Do not try to "find yourself", you must make yourself. Choose what you want to find meaningful and live, create, hate, cry, destroy, fight and die for it.
Do not give in to hope. Remember that nothing you do has any signifiance beyond that with which imbue it. Whatever you do, do it for its own sake. When the universe looks on with indifference, laugh and shout back "fuck you". Remember that to fight meaninglessness is futile, but fight anyway, in spite of and because of its futility. The world may be empty of meaning but it is a blank canvas on which to paint meanings of your own.
Live deliberately. You are free.